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Displaying results 1–5 of 8.
Lupus Mice Express Unique Patterns of MicroRNAs in Lymphocytes: Diagnostic and Therapeutic Importance
Systemic Lupus Erythematosus (SLE) is a life-long, chronic, debilitating autoimmune disease, where the body?s own immune system goes awry and begins to launch devastating inflammatory attack on its own tissues. Lupus belongs to a large category of diseases, referred to as autoimmune diseases, which are considered as one of ...
A Metal-Metal Metathesis Reaction for Trimetallic Nitride Endohedral Metallofullerenes
We have developed a method to replace metal atoms (A) utilizing a metathesis reaction between a fullerene cage with other metal atoms (B) not present in the cage. This process allows the transformation of a more abundant trimetallic nitride endohedral metallofullerene (e.g. A3N@C80A=Sc) to a less abundant trimetallic endohedral ...
Method to Determine and Produce Minimal Binding Motifs Necessary to Create Sub-libraries of Partially Discriminating Antibodies to Significantly Cover a Proteome/genome/metabolome
This invention describes a method to calculate and produce a minimal number of antibodies to span a given -omics space. As an example, we calculate less than ca. 29 antibodies are required to pull down peptides representative of 90% of the human proteome. Furthermore, with our technology, less ...
Chemosensory Evaluation of Training and Oxidative Stress in Long Distance Runners
Oxidative stress has been implicated as the primary reason for a number of human illnesses, such as cardio-pulmonary injury, cancers, diabetes, inflammation, and aging. Athletes, who often submit themselves to training extremes to improve athletic performance, frequently endure complications due to such oxidative stress. Unfortunately it is difficult ...
Branched Peptides as Therapeutics for Structured RNA Targets
In principle, the teriary structure of RNA can provide a scaffold in which molecules can dock and form the necessary intermolecular interactions to become highly selective. The formation of unique three dimensional architecture, often generated through formation of local structures such as bulges, stem-loops, pseudoknots and turns, differentiates RNA ...

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